Iguratimod

DB12233InvestigationalSmall molecule

Iguratimod is under investigation in Rheumatoid Arthritis.

Mechanism: Pharmacologically active on Prostaglandin G/H synthase 2, Macrophage migration inhibitory factor, and E3 ubiquitin ligase TRAF3IP2
Curator reviewed
Formula / weight: C₁₇H₁₄N₂O₆S · 374.37 g/mol (avg)
Code names: T-614

Resolves to

Compound

Structure

InChIKeyANMATWQYLIFGOK-UHFFFAOYSA-NSMILESCS(=O)(=O)NC1=CC2=C(C=C1OC1=CC=CC=C1)C(=O)C(NC=O)=CO2

Targets

What you can answer from here — as of June 15, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

21Clinical trialsPhase, status and sponsor resolved per trial

15+ReferencesStructured and connected to the statements they support

Which drugs share a target with Iguratimod, and which of those have an active Phase 3 trial?

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